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  ATTORNEYS AT LAW   Broomfield, CO
 
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  Palo Alto, CA   San Diego, CA
 
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San Francisco, CA
415 693-2000

August 1, 2006
  www.cooley.com   Washington, DC
202 842-7800
 
       
EDGAR FILING
  GLEN Y. SATO    
 
  (650) 843-5502    
 
  gsato@cooley.com    
 
       
United States
Securities and Exchange Commission
Washington, D.C. 20549
Attn:   Jim B. Rosenberg, Senior Assistant Chief Accountant
 
Re:   Dynavax Technologies Corporation (“Dynavax”)
Form 10-K/A for the Fiscal Year Ended December 31, 2005
Filed April 7, 2006
File No. 000-50577
Dear Mr. Rosenberg:
In response to your letter dated July 27, 2006 directed to Deborah Smeltzer, Vice President Operations and Chief Financial Officer of Dynavax, we have amended our filing on the enclosed Form 10-K/A filed herewith and prepared the following response to your comment:
1. Our revised Form 10-K/A for the fiscal year ended December 31, 2005 has been filed in its entirety, together with the complete Section 302 certifications. This submission is in accordance with the guidance set forth in Question 17 of the Division of Corporation Finance-Sarbanes Oxley Act of 2002, Frequently Asked Questions, dated November 8, 2002 as revised November 14, 2002.
If you have additional questions or comments with respect to this filing, please do not hesitate to contact the undersigned counsel for Dynavax, at (650) 843-5502.
         
Sincerely,
 
   
/s/ Glen Y. Sato      
Glen Y. Sato     
 
cc:     Dynavax:  D. Smeltzer, J. Lew
Cooley Godward:  R. Jones, S. Coates